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Contraindicated (1)pentobarbital will decrease the extent or effect of lumefantrine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Coadministration with solid CYP3A4 inducers may end up in decreased serum concentrations and lack of antimalarial efficacyKeep track of Closely (two)pentobarbital will decrease the level or e